Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human startle reflex: technique and criteria for abnormal response.

S Chokroverty1, T Walczak, W Hening

  • 1Neurology Service, Department of Veterans Affairs Medical Center, Lyons, NJ.

Electroencephalography and Clinical Neurophysiology
|August 1, 1992
PubMed
Summary

This study establishes quantitative norms for the audiogenic startle response and its habituation. Proposed criteria identify abnormal startle responses, aiding in diagnosing conditions like hyperekplexia.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

World Association of Sleep Medicine (WASM) 2016 standards for recording and scoring leg movements in polysomnograms developed by a joint task force from the International and the European Restless Legs Syndrome Study Groups (IRLSSG and EURLSSG).

Sleep medicine·2016
Same author

Chloroplast translocations induced by light pulses : Effects of single light pulses.

Planta·2013
Same author

Chloroplast translocations in Lemna trisulca L. induced by continuous irradiation and by light pulses : Kinetic analysis.

Planta·2013
Same author

Blue-light-induced chloroplast orientation in Mougeotia. Evidence for a separate sensor pigment besides phytochrome.

Planta·2013
Same author

Sleep and breathing in neuromuscular disorders.

Handbook of clinical neurology·2010
Same author

Overview of sleep & sleep disorders.

The Indian journal of medical research·2010

Area of Science:

  • Neuroscience
  • Physiology

Background:

  • Quantitative norms for normal audiogenic startle response habituation are lacking.
  • Understanding startle response habituation is crucial for neurological assessments.

Purpose of the Study:

  • To develop a technique for eliciting and analyzing the audiogenic startle response and its habituation.
  • To establish quantitative criteria for identifying abnormally exaggerated startle responses.

Main Methods:

  • Utilized binaural 105 dB tones in 5 blocks with decreasing inter-stimulus intervals.
  • Compared startle response and habituation in 8 normal subjects versus a patient with exaggerated startle.
  • Measured response duration and rectified EMG area under the curve for orbicularis oculi.

Main Results:

Related Experiment Videos

  • Proposed criteria for abnormal startle include excessive duration, persistence of extracranial responses, and reduced habituation.
  • The patient exhibited abnormal measures across all proposed criteria.
  • Findings align with qualitative reports linking abnormal startle to hyperekplexia.

Conclusions:

  • The developed technique and proposed criteria offer a quantitative method for assessing startle response abnormalities.
  • Further studies with hyperekplexia patients are needed to validate these criteria.
  • This research contributes to the objective diagnosis of neurological conditions involving exaggerated startle reflexes.