The range of sensors and algorithms used in rate adaptive cardiac pacing

Implantable sensors play an important role in physiological cardiac pacing. Sensors can be classified according to the technical methods in which sensing is achieved: the sensing of the evoked ventricular response, intrathoracic impedance and body acceleration forces, and the incorporation of special sensors on pacing electrodes. These sensors differ in their relative merits in terms of speed, proportionality, sensitivity, and specificity of rate response. The efficacy of a sensor can be significantly modified by the algorithm used in relating sensor signal to a pacing rate change. The currently available types of sensors and algorithms are summarized and compared in this review article. The relative merits of these sensors and algorithms form the basis for designing a multisensor pacing system.