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Updated: Aug 15, 2026

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Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Isochromosome 1q in acute monocytic leukemia: a new nonrandom association
J M Hawkins1, M Wood, F Wright
1Department of Haematology, Royal Free Hospital and Medical School, London, United Kingdom.
Genes, Chromosomes & Cancer
|September 1, 1992
Abstract:
We report a case of de novo acute monocytic leukemia in a 25-year-old man in whom the sole clonal cytogenetic abnormality was an additional isochromosome 1q. Cytogenetic polymorphisms indicate that, in addition to the formation of the isochromosome, a duplication of the remaining normal chromosome 1 had taken place. Other reported cases suggest an association between acute monocytic leukemia and i(1q).

