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Nodular sclerosing Hodgkin's disease and large cell lymphoma. Immunophenotypic characterization of a composite case
1Department of Anatomical Pathology, University of Pavia, I.R.C.C.S. Policlinico S. Matteo, Italy.
Virchows Archiv. A, Pathological Anatomy and Histopathology
|January 1, 1992
Abstract:
Composite lymphomas have rarely been reported in Hodgkin's disease (HD), except in the lymphocyte predominance sub-type, and immunohistochemical investigations have been performed in only few cases. We describe the histological and immunophenotypical findings in a case of composite nodular sclerosing HD and high-grade, large cell non-Hodgkin's lymphoma (NHL). In our case HD and NHL cells displayed striking morphological and immunophenotypical divergence, suggesting a lack of correlation between the two neoplasms.