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Impaired iron status in rats as induced by copper deficiency
G J Van Den Berg1, F Van Houwelingen, A G Lemmens
1Interfaculty Reactor Institute, University of Technology, Delft, The Netherlands.
Biological Trace Element Research
|October 1, 1992
Abstract:
The hypothesis was tested that marginal copper deficiency affects iron status. Copper restriction (1 vs 5 mg Cu/kg diet) significantly lowered iron concentrations and transferrin saturation in plasma and reduced blood hemoglobin, hematocrit, and iron concentrations in tibia and femur, but raised iron concentrations in liver. Marginal copper deficiency did not affect feed intake and bodyweight gain.