Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changes in the erythrocyte sodium pump with age.

G J Naylor, D A Dick, E P Worrall

    Gerontology
    |January 1, 1977
    PubMed
    Summary

    Erythrocyte sodium concentration increases with age in females, linked to decreased active transport and increased passive transport. This change is associated with a decline in erythrocyte Na-K ATPase activity in older women.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Germline Cancer Testing in Unselected Patients with Gastric and Esophageal Cancers: A Multi-center Prospective Study.

    Digestive diseases and sciences·2022
    Same author

    Weather and livestock risk factors for Escherichia coli O157 human infection in Alberta, Canada.

    Epidemiology and infection·2014
    Same author

    Assessing the existing information on the efficacy of bovine vaccination against Escherichia coli O157:H7--a systematic review and meta-analysis.

    Zoonoses and public health·2012
    Same author

    Effects of feed treatment and gender on the flavour and texture profiles of cured and uncured pork cuts. I. Ractopamine treatment and dietary protein level.

    Meat science·2011
    Same author

    The effects of feed treatment and gender on the flavour and texture profiles of cured and uncured pork cuts. III. Effects of gender.

    Meat science·2011
    Same author

    Effects of acclimation temperature on thermal tolerance, locomotion performance and respiratory metabolism in Acheta domesticus L. (Orthoptera: Gryllidae).

    Journal of insect physiology·2010

    Area of Science:

    • Physiology
    • Gerontology
    • Biochemistry

    Background:

    • The erythrocyte sodium pump plays a crucial role in maintaining cellular ion balance.
    • Age-related changes in cellular transport mechanisms are not fully understood.
    • Investigating the erythrocyte sodium pump provides insights into age-associated physiological alterations.

    Purpose of the Study:

    • To estimate erythrocyte sodium pump activity in adult subjects.
    • To investigate age-related changes in erythrocyte sodium concentration and transport.
    • To determine the relationship between erythrocyte Na-K ATPase activity and aging in different sexes.

    Main Methods:

    • Estimation of erythrocyte sodium concentration.
    • Measurement of erythrocyte active and passive transport.
    • Assessment of erythrocyte Na-K ATPase activity.
    • Analysis of data stratified by sex and age.

    Main Results:

    • Erythrocyte sodium concentration increased with age in females, but not males.
    • Erythrocyte active transport decreased with age in females.
    • Erythrocyte passive transport increased with age in females, correlating with sodium concentration changes.
    • Erythrocyte Na-K ATPase activity decreased with age in females, explaining the active transport changes.

    Conclusions:

    • Age-related decline in erythrocyte Na-K ATPase activity contributes to altered sodium transport in older females.
    • Sex-specific differences exist in age-related erythrocyte sodium regulation.
    • These findings highlight potential physiological adaptations in erythrocyte ion transport with aging.

    Related Experiment Videos