[Interventional radiology in the treatment of acute and chronic mesenteric ischemia]

G Simonetti1, L Lupattelli, F Urigo

  • 1Istituto di Radiologia, II Università di Roma Tor Vergata.

Insights

Percutaneous transluminal angioplasty (PTA) and fibrinolysis offer effective radiologic revascularization for visceral artery diseases. These minimally invasive treatments show high success rates for acute and chronic mesenteric ischemia, providing a valuable alternative to surgery.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Gastroenterology

Background:

  • Visceral artery stenoses and occlusions pose significant clinical challenges.
  • Surgical intervention carries inherent risks for treating these conditions.

Purpose of the Study:

  • To evaluate the efficacy of radiologic revascularization, specifically percutaneous transluminal angioplasty (PTA) and fibrinolysis, for visceral artery diseases.
  • To assess treatment outcomes for patients with acute and chronic mesenteric ischemia.

Main Methods:

  • Retrospective analysis of 32 patients with visceral artery conditions.
  • Treatment modalities included PTA (using Grüntzig, Cobra, or Simmons balloons) and fibrinolysis (urokinase or rtPA).
  • Papaverine infusion was used for non-occlusive acute mesenteric ischemia.

Main Results:

  • Successful treatment in 80% of acute mesenteric ischemia cases, with 4 out of 5 patients experiencing symptom remission.
  • PTA achieved a technical success rate of 85-95% in 22 patients with chronic mesenteric ischemia.
  • A 10% restenosis rate was observed at 24 months for chronic cases.

Conclusions:

  • Radiologic revascularization, including PTA and fibrinolysis, is a highly effective treatment for visceral artery stenoses and occlusions.
  • These minimally invasive procedures offer excellent therapeutic results and can be widely applied.
  • PTA, potentially combined with loco-regional fibrinolytic therapy, represents a valuable alternative to surgery.

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