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Autoreactive cytotoxic cells in rabbits after prolonged immunostimulation
F Galdiero1, C Romano Carratelli, I Nuzzo
1Istituto di Microbiologia, I Facoltà di Medicina e Chirurgia, Università di Napoli, Italy.
FEMS Microbiology Immunology
|July 1, 1992
Abstract:
Rabbits immunized for 6 months with different amounts of sterile human serum showed weight loss and a decrease in leukocytes. The lymphocyte population reacting to ConA contained autoreactive cells capable of causing 51Cr release from labeled cells from a culture consisting of splenic and peripheral lymphocytic cells from the same animal.