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Related Experiment Videos

Peristomal pyoderma gangrenosum.

M Keltz1, M Lebwohl, S Bishop

  • 1Mount Sinai Medical Center, New York, NY 10029.

Journal of the American Academy of Dermatology
|August 1, 1992
PubMed
Summary
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Intralesional steroid injections offer a rapid and effective treatment for peristomal pyoderma gangrenosum in Crohn's disease patients. This method is convenient, not interfering with ostomy appliance adhesion.

Area of Science:

  • Gastroenterology
  • Dermatology
  • Surgical Ostomy Care

Background:

  • Crohn's disease (CD) is a chronic inflammatory bowel disease.
  • Peristomal pyoderma gangrenosum (PPG) is a rare, ulcerative complication occurring around ostomy sites.
  • Management of PPG can be challenging, particularly in CD patients.

Observation:

  • A unique case of a Crohn's disease patient with peristomal pyoderma gangrenosum is presented.
  • The patient exhibited a rapid and positive response to intralesional steroid injections.
  • This treatment approach was well-tolerated and did not compromise ostomy appliance adherence.

Findings:

  • Intralesional corticosteroid injection is an effective therapeutic option for peristomal pyoderma gangrenosum.
  • The intermittent administration aligns with ostomy appliance changes, enhancing patient convenience.

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  • Review of 11 literature cases supports the efficacy and practicality of this treatment modality.

    • Implications:

    • Intralesional steroids represent an ideal treatment for peristomal pyoderma gangrenosum, especially in inflammatory bowel disease patients.
    • This minimally invasive approach offers a localized and effective solution with practical benefits for ostomy care.
    • Further investigation into localized therapies for peristomal pyoderma gangrenosum is warranted.