[Immunological study of acute forms of acne]

In severe forms of acne (grade IV) there is probably an inmunological alteration consisting of: 1) Alterations in the IgG. 2) They may be produced in small quantity or destroyed more rapidly. 3) Cellular immunity is normal using PHA and diminished with habitual tests. 4) It is necessary to normalize these globulin levels before or during specific medication, with antibiotics or sulfa drugs. 5) Essential aminoacids should be given so as to raise the inmunoglobulins to normal levels. The administration of commercial inmunoglobulins should be avoided, because, for genetic reason, they could produce autoimmunity or isosensibility and diminished the levels one is trying to raise.