Related Experiment Video
Updated: Aug 15, 2026

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
Published on: June 10, 2013
Stress-induced block of milk ejection
A simple method has been described by which the action of drugs on the stress-induced block in milk ejection can be investigated on lactating guinea-pigs. Reserpine, meprobamate and chlorpromazine when administered to the lactating mother at various periods before suckling reduced the block in milk ejection caused by the stress. Dibenamine and dichloroisoprenaline did not affect in any way the stress-induced block. It is suggested that the stress-induced block in milk ejection is probably a nervous block and not mediated through adrenaline.
A simple method has been described by which the action of drugs on the stress-induced block in milk ejection can be investigated on lactating guinea-pigs. Reserpine, meprobamate and chlorpromazine when administered to the lactating mother at various periods before suckling reduced the block in milk ejection caused by the stress. Dibenamine and dichloroisoprenaline did not affect in any way the stress-induced block. It is suggested that the stress-induced block in milk ejection is probably a nervous block and not mediated through adrenaline.
Related Concept Videos
Neuromuscular Junction And Blockade
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Intestinal Phase of Digestion
The arrival of the chyme in the small intestine distends the duodenum, which triggers the enterogastric reflex. This distension...
Intestinal Obstruction II: Pathophysiology

