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Related Experiment Videos

Reoperation and the centrifugal pump?

H Jakob1, G Hafner, S Iversen

  • 1Division of Cardiothoracic and Vascular Surgery, Johannes Gutenberg University, Mainz, FRG.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

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Centrifugal blood pumps may offer benefits over roller pumps in long cardiac surgeries, showing reduced plasma hemoglobin and improved platelet counts. However, roller pumps remain safe for standard cardiac procedures.

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering

Background:

  • Postperfusion syndrome remains a challenge in lengthy cardiac operations utilizing extracorporeal circulation (ECC).
  • Evaluating alternative blood pumping technologies is crucial for improving patient outcomes.

Purpose of the Study:

  • To compare the efficacy of centrifugal versus roller pumps in reducing blood cell damage during open-heart surgery.
  • To assess the impact of different arterial blood pumps on markers of coagulation and fibrinolysis.

Main Methods:

  • A randomized prospective study involving 50 patients undergoing elective coronary artery bypass grafting.
  • Patients were divided into two groups: one using a centrifugal pump (Biomedicus) and the other a roller pump (Stöckert).
  • Blood samples were analyzed for cellular elements, PMN-elastase, plasma hemoglobin, beta-thromboglobulin, thrombin-antithrombin III complex, and D-dimer.

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Main Results:

  • No significant differences were observed in bypass time, ECC flow, fluid balance, or clinical outcomes between the groups.
  • The centrifugal pump group showed significantly lower plasma hemoglobin, beta-thromboglobulin, and D-dimer levels (P<0.05).
  • Platelet counts were also higher in the centrifugal pump group (P<0.5), with differences becoming significant after 90 minutes of bypass.

Conclusions:

  • Centrifugal pumps may offer advantages in preserving blood components during extended extracorporeal circulation.
  • Roller pumps are still considered safe and effective for standard cardiac surgical procedures.
  • Further research into ECC-time-dependent effects of blood pumps is warranted.