Disseminated intravascular coagulation

In normal hemostasis, a balance exists between coagulation and fibrinolysis. Disseminated intravascular coagulation (DIC) is a condition characterized by the excessive formation of fibrin clots; it involves all aspects of the coagulation system. In view of its potential for major morbidity and mortality, an understanding of the disorder is essential. Management of DIC in pregnancy should include removal of the triggering mechanism and aggressive blood and fluid replacement.