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[Anorectal manometry in Hirschsprung disease].
J M Gil Vernet1, J M Casasa, J Lloret
1Departamento de Cirugía, Hospital Materno-Infantil Vall d'Hebrón, Barcelona.
Summary
The absence of the anal inhibitory reflex (AIR) via ano-rectal manometry is crucial for diagnosing Hirschsprung
Area of Science:
- Pediatric Gastroenterology
- Colorectal Surgery
- Diagnostic Imaging
Context:
- Hirschsprung's disease diagnosis relies on identifying the absence of the anal inhibitory reflex (AIR).
- Ano-rectal manometry is a key diagnostic tool for assessing AIR.
- This study evaluated the diagnostic accuracy of AIR in a large patient cohort.
Purpose:
- To determine the diagnostic significance of absent anal inhibitory reflex (AIR) in Hirschsprung's disease.
- To assess the accuracy of ano-rectal manometry in identifying Hirschsprung's disease.
- To evaluate the incidence of false negatives and positives in AIR testing.
Summary:
- A study of 199 patients (0-1 month and 1 month to 50 years) investigated the absence of the anal inhibitory reflex (AIR) using ano-rectal manometry.
- AIR was absent in 88 patients and present in 111. Histologic confirmation identified 86 cases of Hirschsprung's disease.
- The study reported a low error rate of 0.5% (1 false negative), highlighting the reliability of AIR testing.
Impact:
- Establishes ano-rectal manometry and the anal inhibitory reflex (AIR) as highly accurate diagnostic methods for Hirschsprung's disease.
- Provides crucial data on the diagnostic performance of AIR testing across a wide age range.
- Contributes to improved diagnostic strategies, potentially reducing misdiagnosis and improving patient outcomes.