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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Peptic Ulcer Disease I: Introduction

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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Pemphigus vegetans in a child.

J H Sillevis Smitt1, T J Mulder, F W Albeda

  • 1Department of Dermatology, University of Amsterdam, The Netherlands.

The British Journal of Dermatology
|September 1, 1992
PubMed
Summary
This summary is machine-generated.

This is the first reported case of juvenile pemphigus vegetans, a rare skin condition. Traditional Chinese herbal medicine provided excellent results when conventional treatments were refused.

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Area of Science:

  • Dermatology
  • Autoimmune Blistering Diseases
  • Traditional Chinese Medicine

Background:

  • Pemphigus vegetans is a rare variant of pemphigus vulgaris, an autoimmune blistering disease.
  • Juvenile onset of pemphigus vegetans is exceptionally uncommon.
  • Diagnosis requires thorough clinical, histopathological, and immunohistological evaluation.

Observation:

  • A 12-year-old boy presented with clinical, histopathological, and immunohistological findings consistent with pemphigus vegetans.
  • Conventional treatments including prednisone and azathioprine were declined by the patient.
  • Treatment was initiated using a decoction of herbs from traditional Chinese medicine.

Findings:

  • The patient achieved excellent clinical results with the traditional Chinese herbal medicine.
  • This represents the first documented case of juvenile pemphigus vegetans in the medical literature.
  • The study discusses potential active components within the herbal decoction responsible for the therapeutic effect.

Implications:

  • This case highlights the potential efficacy of traditional Chinese herbal medicine in managing pemphigus vegetans, particularly in pediatric cases.
  • Further research into the active components of this herbal decoction may reveal novel therapeutic strategies for autoimmune blistering diseases.
  • The findings suggest a need to consider complementary and alternative medicine approaches in refractory or treatment-intolerant cases of pemphigus vegetans.