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Infantile hypertrophic pyloric stenosis in Ghana

J F Tandoh1, A A Hesse

  • 1Department of Surgery, Korle Bu Teaching Hospital, Accra, Ghana.

West African Journal of Medicine
|April 1, 1992
PubMed

Insights

This study on hypertrophic pyloric stenosis in Ghanaian infants found a high male-to-female ratio and common presentation within the first six weeks of life. Operative mortality was 3.6% in this pediatric surgical condition.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Epidemiology

Background:

  • Hypertrophic pyloric stenosis (HPS) is a common cause of non-bilious vomiting in infants.
  • Understanding the epidemiological characteristics of HPS is crucial for early diagnosis and management.

Purpose of the Study:

  • To describe the clinical presentation and outcomes of hypertrophic pyloric stenosis in Ghanaian infants.
  • To determine the incidence ratio, associated conditions, and mortality rates of HPS in the studied population.

Main Methods:

  • Retrospective analysis of 84 infants diagnosed with HPS between 1974 and 1988.
  • Data collection on patient demographics, clinical features, associated anomalies, and operative outcomes.

Main Results:

  • A male-to-female incidence ratio of 9:1 was observed.
  • First-born infants accounted for 23.8% of cases.
  • Congenital anomalies and jaundice were present in 10.7% and 3.6% of infants, respectively.
  • Vomiting onset occurred within the first week of life in 33.3% of infants.
  • Peak age for presentation and diagnosis was 2-6 weeks.
  • Operative mortality was 3.6%.

Conclusions:

  • Hypertrophic pyloric stenosis in Ghanaian infants exhibits a strong male predominance and typical presentation within the first six weeks of life.
  • The study highlights the importance of recognizing associated anomalies and timely surgical intervention to minimize mortality.

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