Related Experiment Videos
Acute intermittent [corrected] porphyria. An often forgotten diagnosis in acute abdomen
S K Owusu1, E O Asamoah, V A Ofori-Darko
1University of Ghana Medical School, Accra.
West African Journal of Medicine
|April 1, 1992
Abstract:
Three cases of Acute Intermittent Porphyria (AIP) are described. All presented with acute intermittent abdominal pains. One had grand-mal epilepsy as well. Two were diagnosed by chance. In the third case the diagnosis was thought of. It is suggested that AIP should always be considered as one of the differential diagnosis in Acute Abdomen in West Africa.
Insights
Acute Intermittent Porphyria (AIP) can cause severe abdominal pain and neurological symptoms. Early consideration of AIP is crucial for diagnosing acute abdomen cases in West Africa.
Area of Science:
- Internal Medicine
- Neurology
- Genetics
Background:
- Acute Intermittent Porphyria (AIP) is a rare genetic disorder affecting heme biosynthesis.
- It is characterized by intermittent attacks of severe symptoms.
Observation:
- Three cases of AIP presenting with acute, intermittent abdominal pain are detailed.
- One patient also experienced grand-mal epilepsy.
- Two diagnoses were incidental, while one was suspected.
Findings:
- The study highlights the varied clinical presentations of AIP.
- Diagnostic challenges in resource-limited settings are implied.
Implications:
- Acute Intermittent Porphyria should be included in the differential diagnosis for acute abdomen in West Africa.
- Increased awareness can lead to earlier diagnosis and management of AIP.