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All-trans retinoic acid in acute promyelocytic leukemia: preliminary results in Cuba
P Hernández1, J Carnot, E Dorticós
1Instituto de Hematologia e Inmunologia, Ciudad de La Habana, Cuba.
Annals of Hematology
|September 1, 1992
Abstract:
Seven patients with acute promyelocytic leukemia (APL) were treated with all-trans retinoic acid (ATRA). Five (71.4%) achieved complete remission (CR). Most side effects were transient and well tolerated. Hyperleukocytosis was the major adverse effect. These observations confirm the efficacy of ATRA for inducing CR in APL.