Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Potential clinical applications for blood substitutes.

R M Winslow1

  • 1Department of Medicine, University of California, San Diego 92093.

Biomaterials, Artificial Cells, and Immobilization Biotechnology : Official Journal of the International Society for Artificial Cells and Immobilization Biotechnology
|January 1, 1992
PubMed
Summary

Oxygen-carrying blood substitutes are nearing clinical use, offering alternatives to human blood transfusions. Their safety and efficacy will determine the widespread adoption of these innovative medical products.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Forward Modeling of Coronal Mass Ejection Flux Ropes in the Inner Heliosphere with 3DCORE.

Space weather : the international journal of research & applications·2018
Same author

Factors Affecting the Geo-effectiveness of Shocks and Sheaths at 1 AU.

Journal of geophysical research. Space physics·2018
Same author

Modeling observations of solar coronal mass ejections with heliospheric imagers verified with the Heliophysics System Observatory.

Space weather : the international journal of research & applications·2017
Same author

CO-MP4, a polyethylene glycol-conjugated haemoglobin derivative and carbon monoxide carrier that reduces myocardial infarct size in rats.

British journal of pharmacology·2008
Same author

A randomized, single-blind, increasing dose safety trial of an oxygen-carrying plasma expander (Hemospan) administered to orthopaedic surgery patients with spinal anaesthesia.

Transfusion medicine (Oxford, England)·2008
Same author

Current status of oxygen carriers ('blood substitutes'): 2006.

Vox sanguinis·2006

Area of Science:

  • Biomedical Engineering
  • Hematology
  • Physiology

Background:

  • Homologous blood transfusions carry risks, including viral disease transmission (HIV, hepatitis) and transfusion reactions.
  • The collection and storage of human blood are expensive and resource-intensive.
  • Advancements in biomedical engineering are driving the development of artificial oxygen carriers.

Purpose of the Study:

  • To discuss the anticipated clinical applications of oxygen-carrying blood substitutes.
  • To highlight the factors influencing the adoption of these novel products.
  • To explore the potential of blood substitutes in advancing oxygen transport physiology research.

Main Methods:

  • Review of current research and development in blood substitute technology.

Related Experiment Videos

  • Analysis of potential clinical use cases and their projected impact.
  • Discussion of safety considerations and their role in product acceptance.

    • Main Results:

    • Oxygen-carrying blood substitutes are expected to be available for clinical use within the next decade.
    • Anticipated clinical applications are numerous and likely to expand.
    • Product safety is a critical determinant of widespread clinical adoption.

    Conclusions:

    • Blood substitutes offer a promising alternative to homologous blood transfusions, mitigating risks and costs.
    • Further research into safety and efficacy is crucial for successful clinical integration.
    • These products hold significant potential for both clinical practice and fundamental physiological research.