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Brain neurite-stimulating protein promotes formation of mechanosensory endings in sensory neuron
G N Akoev1, O S Sotnikov, N I Chalisova
1Pavlov Institute of Physiology, Russian Academy of Sciences, St. Peterburg.
Neuroreport
|June 1, 1992
Abstract:
In the present study we have shown that in the organotypic culture of dorsal root ganglia (DRG) of 10-11 day-old chick embryos, the neurite-stimulating protein (NSP) from bovine brain promotes the development of branching mechanosensory endings. The light and electron microscopic observation revealed that the morphological features of these sensory endings are similar to those in vivo. A mechanical stimulation of these endings elicited bursts of impulses in the sensory neurons.