[Reduction of voluntary alcohol consumption under the effects of prolonged-action zinc]

A V Skal'nyĭ, E N Kukhtina, I P Ol'khovskaia

Biulleten' Eksperimental'Noi Biologii I Meditsiny

|April 1, 1992

Abstract:

It was revealed that an involuntary rats' intoxication with 10% ethanol solution during 8 months caused a reduction of zinc content in the brain. A subcutaneous depot administration of highly dispersed zinc powder in a dose of 5 mg/kg reduced ethanol consumption under conditions of free choice for two weeks. This effect of the preparation was associated with normalization of zinc content and increase of a malondialdehyde level in the brain.

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Abstract:

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