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Related Experiment Videos

An augmented regenerative technique for severe osseous defects.

V J Iacono1, K Demerel, S M Zove

  • 1State University of New York at Stony Brook.

Periodontal Clinical Investigations : Official Publication of the Northeastern Society of Periodontists
|January 1, 1992
PubMed
Summary

Guided tissue regeneration using a soft tissue patch and hydroxylapatite shows promise for treating severe periodontal defects. This technique aids in new attachment and bone regeneration in challenging cases.

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Area of Science:

  • Periodontology
  • Regenerative Medicine

Background:

  • Guided tissue regeneration (GTR) with barrier membranes is established for treating severe osseous defects and furcation involvement.
  • Existing membranes and techniques were evaluated to develop an improved GTR procedure.

Purpose of the Study:

  • To develop and evaluate a novel GTR technique using an expanded polytetrafluoroethylene (ePTFE) soft tissue patch and hydroxylapatite (HA) bone substitute.
  • To assess the efficacy of this combined approach in maintaining space for blood clot maturation and promoting new attachment.

Main Methods:

  • A procedure was developed utilizing a 1 mm thick ePTFE soft tissue patch in conjunction with an alloplast hydroxylapatite bone substitute (HA-500).
  • An in vitro study assessed microbial adherence of Streptococcus sanguis and Actinomyces viscosus to the ePTFE patch compared to standard Gore-Tex Periodontal Material.

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  • Two case reports documented the clinical application of the ePTFE patch and HA in patients with furcation involvement and severe vertical osseous defects.

    • Main Results:

    • The in vitro study demonstrated significantly lower adherence of Streptococcus sanguis (P < .005) and Actinomyces viscosus (P < .025) to the ePTFE soft tissue patch compared to Gore-Tex Periodontal Material.
    • Case reports indicated successful outcomes in patients treated with the ePTFE patch augmented with hydroxylapatite, showing evidence of new attachment and regeneration.

    Conclusions:

    • The combination of an ePTFE soft tissue patch and hydroxylapatite is a viable and effective method for GTR in treating severe periodontal osseous defects and furcation involvement.
    • This technique may offer advantages in reducing bacterial adherence and promoting a favorable environment for periodontal regeneration.