Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Macrodystrophia lipomatosa: radiographic observations.

S K Gupta1, O P Sharma, S V Sharma

  • 1Department of Diagnostic Radiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

The British Journal of Radiology
|September 1, 1992
PubMed
Summary

Macrodystrophia lipomatosa (MDL) involves overgrowth of fat and bone in digits, presenting diverse radiographic features. This study details 23 cases, highlighting typical and uncommon skeletal and soft tissue changes in MDL.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Can I Interview Her? Gatekeeping in a Telephone Survey of Female Migrants in India.

Survey practice·2025
Same author

An Indian Consensus on Sarcopenia: Epidemiology, Etiology, Clinical Impact, Screening, and Therapeutic Approaches.

International journal of general medicine·2025
Same author

Gone and Forgotten? Predictors of Birth History Omissions in India.

Demographic research·2024
Same author

Tuberculosis in elderly persons.

The Indian journal of tuberculosis·2022
Same author

Diagnoses and management of adult cough: An Indian Environmental Medical Association (EMA) position paper.

Respiratory medicine·2020
Same author

First Report on Association of Colletotrichum coccodes with Chili Anthracnose in India.

Plant disease·2019

Area of Science:

  • Radiology
  • Orthopedics
  • Medical Imaging

Background:

  • Macrodystrophia lipomatosa (MDL) is a rare congenital condition characterized by progressive, localized overgrowth of adipose and mesenchymal tissues.
  • The radiographic manifestations of MDL can be varied, making diagnosis challenging.

Purpose of the Study:

  • To comprehensively describe the spectrum of radiographic findings in 23 cases of macrodystrophia lipomatosa.
  • To identify typical and uncommon radiological features associated with MDL.

Main Methods:

  • Retrospective review of radiographic imaging (X-rays, angiography) from 23 patients diagnosed with MDL.
  • Detailed analysis of bone morphology, soft tissue hypertrophy, and associated anomalies.

Main Results:

Related Experiment Videos

  • Typical findings included mesodermal tissue hypertrophy, particularly fat overgrowth, and enlarged phalanges and metatarsals.
  • Uncommon features observed were elongated and thinned bones, small phalanges/metatarsals, slanting articular surfaces, syndactyly, polydactyly, brachydactyly, and symphalangism.
  • Palmar, plantar, forearm, and leg involvement occurred in a significant number of cases; angiography was non-specific.

Conclusions:

  • Macrodystrophia lipomatosa exhibits a wide range of radiographic presentations, with digital involvement being most common.
  • Radiographic evaluation is crucial for characterizing MDL, though findings can be diverse and include rare anomalies.