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Updated: Sep 6, 2026

Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Mediastinal vascular anomalies causing tracheal and esophageal compression and obstruction in childhood
Insights
This study reviewed 22 pediatric surgeries for vascular compression of the trachea and esophagus, identifying common causes like double aortic arch. Careful pre- and post-operative care is crucial for these serious cases.
Area of Science:
- Pediatric Surgery
- Thoracic Surgery
- Vascular Anomalies
Background:
- Vascular compression of the trachea and esophagus in children can lead to severe respiratory and swallowing difficulties.
- Congenital anomalies of the aortic arch are a significant cause of such compressions.
- Surgical intervention is often necessary to alleviate symptoms and prevent long-term complications.
Purpose of the Study:
- To review surgical outcomes for pediatric patients with vascular compression of the airway and esophagus.
- To identify the common vascular anomalies causing these compressions.
- To highlight the importance of perioperative management in improving patient survival.
Main Methods:
- Retrospective review of 22 pediatric cases operated for vascular compression over 11 years.
- Classification of vascular anomalies including double aortic arch, right aortic arch with left ligamentum arteriosum, anomalous innominate artery, and aberrant right subclavian artery.
- Analysis of surgical outcomes, complications, and mortality.
Main Results:
- 22 children underwent surgery for vascular compression.
- The most frequent anomaly was double aortic arch (13 cases).
- One unusual case of right aortic arch, aberrant left subclavian artery, and left ligamentum arteriosum was reported.
- Mortality rate was 18% (4 deaths), with one intraoperative death during intubation and three postoperative deaths despite tracheotomy.
Conclusions:
- Vascular compression of the trachea and esophagus in children presents significant surgical challenges.
- Careful preoperative and postoperative management is essential for improving outcomes.
- Avoiding tracheotomy when possible may reduce postoperative complications and mortality.
Abstract:
Over an 11-year period, 22 children have been operated upon at the Hospital for Sick Children, Toronto, for vascular compression of the trachea and esophagus. Thirteen had a double aortic arch; three, a right aortic arch and left ligamentum arteriosum; three, an anomalous innominate artery; and one, an aberrant right subclavian artery. An unusual case of right aortic arch, aberrant left subclavian artery and left ligamentum arteriosum is reported for the first time. One child with an anomalous left pulmonary artery producing emphysema of the right lung is also described. One death occurred during the process of intubation, and three patients died postoperatively despite tracheotomy. These children were in serious condition, and the importance of rigid preoperative and postoperative care, avoiding tracheotomy if possible, is emphasized.
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