Related Experiment Video
Updated: Jul 29, 2026
09:43
An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
Published on: March 30, 2018
Non-Hodgkin's lymphoma and occupational exposure
P A Scherr1, G B Hutchison, R S Neiman
1Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115.
Cancer Research
|October 1, 1992
Summary
Certain occupations significantly increase non-Hodgkin
Area of Science:
- Epidemiology
- Occupational Health
- Oncology
Background:
- Non-Hodgkin's lymphoma (NHL) is a heterogeneous group of lymphoid malignancies.
- Understanding occupational risk factors is crucial for targeted prevention strategies.
Purpose of the Study:
- To investigate the association between specific occupational exposures and the risk of developing non-Hodgkin's lymphoma.
Main Methods:
- A case-control study design was employed.
- 303 newly diagnosed NHL patients and 303 matched controls from the Boston metropolitan area were interviewed.
- Data on occupational history and potential exposures were collected.
Main Results:
- Increased risk of NHL was observed in agriculture, forestry, and fishing (RR=3.0), construction (RR=2.1), and leather industries (RR=2.1).
- Specific job roles like plant farmers/gardeners (RR unbounded), painters/plasterers (RR=6.0), and tradespeople (carpenters, masons, plumbers, roofers) (RR=12.0) showed elevated risks.
- Findings suggest a potential link between NHL and exposure to chlorophenols or phenoxyacetic acids.
Conclusions:
- Occupational exposures in specific industries and job roles are associated with an increased risk of non-Hodgkin's lymphoma.
- Further research into specific chemical exposures, such as chlorophenols and phenoxyacetic acids, is warranted.
Related Concept Videos
02:59Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
01:15Secondary Lymphoid Organs
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
01:29Pulmonary Tuberculosis I
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
01:28Pulmonary Tuberculosis II
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
01:31Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories: