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Related Experiment Videos

[Transitory hyperphosphatasemia in childhood].

D Behúlová1, V Bzdúch, V Lehotská

  • 1Oddelenie klinickej biochémie Detskej fakultnej nemocnice, Bratislava.

Ceskoslovenska Pediatrie
|September 1, 1992
PubMed
Summary

Transient hyperphosphatasaemia, a temporary condition in children, involves elevated serum alkaline phosphatase. This benign finding resolves spontaneously within weeks, avoiding unnecessary medical interventions.

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Area of Science:

  • Pediatric Endocrinology
  • Clinical Biochemistry

Context:

  • Retrospective analysis of 11 children hospitalized between 1985-1990.
  • Focus on 6 children with accurately evaluated serum alkaline phosphatase trends.

Purpose:

  • To describe the clinical characteristics and biochemical profile of transient hyperphosphatasaemia in children.
  • To highlight the importance of recognizing this benign condition to prevent unnecessary investigations.

Summary:

  • Transient hyperphosphatasaemia was incidentally detected in hospitalized children.
  • Elevated serum alkaline phosphatase (5-15 fold above normal) normalized spontaneously within 3-12 weeks.
  • A typical isoenzyme pattern with a high ratio of thermolabile isoenzyme was observed.

Impact:

  • Recognition of transient hyperphosphatasaemia can prevent unnecessary diagnostic procedures and associated costs.
  • Understanding this condition aids in accurate diagnosis and appropriate patient management.
  • Contributes to the literature on pediatric biochemical abnormalities.

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