[Transformation of a poststreptococcal type glomerulonephritis into a rapidly progessive glomerulonephritis (author's...

In the morphological course of a poststreptococcal type glomerulonephritis in a 37-year old patient without evidence of streptococcal infection crescents of Bowman's capsule developed after 4 months. The clinical course was rapidly progessive (the patient was uremic 5 months after onset) in contrast to the normal fair prognosis of the poststreptococcal type glomerulonephritis. Two renal biopsies were examined at an interval of 4 months. Both showed closely packed immunecomplex deposits (humps) on the glomerular immunecomplex deposits in the poststreptococcal type glomerulonephritis is a prognostically unfavourable sign.