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Updated: Aug 5, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
The Leeds-Keio prosthesis in chronic anterior cruciate deficiency
1Royal Preston Hospital, Lancs., United Kingdom.
Abstract:
A woven polyester graft is used in chronic anterior cruciate instability. Twenty-five patients were reviewed with an average follow-up period of almost five years. The patients were assessed in terms of function, clinical examination, and residual laxity. The results showed that four could be classified as excellent, 16 good, and four poor. Fifty-two percent of patients returned to their preaccident level of activity, and there did not appear to be any evidence of increasing laxity with time. All patients had a good range of flexion with no extension loss. This prosthesis, along with its unique method of fixation, offers a simple alternative to patellar tendon or soft tissue reconstructions in the chronic anterior cruciate-deficient knee.

