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Human liver glutamic gamma-semialdehyde dehydrogenase: structural relationship to the yeast enzyme
1Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, PA 15261.
Abstract:
The amino acid sequences of nine tryptic peptides (containing altogether 105 amino acids) from human liver glutamic gamma-semialdehyde of dehydrogenase (hitherto designated as ALDH4) were found to correspond, at 33-66% identity, to segments from the yeast 1-proline-5-carboxylate (P5C) dehydrogenase encoded by the PUT2 gene.