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Updated: Aug 10, 2026

Measuring the 50% Haemolytic Complement (CH50) Activity of Serum
08:26

Measuring the 50% Haemolytic Complement (CH50) Activity of Serum

Published on: March 30, 2010

[Application of CH50 assay to the detection of circulating immune complexes (author's transl)]

F Santoro, P Wattre, A Capron

    Pathologie-Biologie
    |February 1, 1977
    PubMed

    Detection and titration of circulating immune complexes appear as an essential tool for the diagnosis and prognostic evaluation of immune complex diseases. Authors propose a simple, rapid, senstive and quantitative method based on the evaluation of complement by soluble immune complexes measured by 50% hemolytic activity. This technique was compared to the I125 C1q binding test and may be recommended for clinical laboratory use.

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