Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Glycemic control and diabetic complications.

S Strowig¹, P Raskin

¹Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235-8858.

|September 1, 1992

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The effect of basal-bolus therapy varies with baseline 1,5-anhydroglucitol level in people with Type 2 diabetes: a post hoc analysis.

Diabetic medicine : a journal of the British Diabetic Association·2018

Same author

Effect of adding insulin degludec to treatment in patients with type 2 diabetes inadequately controlled with metformin and liraglutide: a double-blind randomized controlled trial (BEGIN: ADD TO GLP-1 Study).

Diabetes, obesity & metabolism·2016

Same author

AMG 151 (ARRY-403), a novel glucokinase activator, decreases fasting and postprandial glycaemia in patients with type 2 diabetes.

Diabetes, obesity & metabolism·2015

Same author

Pulmonary function over 2 years in diabetic patients treated with prandial inhaled Technosphere Insulin or usual antidiabetes treatment: a randomized trial.

Diabetes, obesity & metabolism·2011

Same author

Glycaemic control with liraglutide: the phase 3 trial programme.

International journal of clinical practice. Supplement·2010

Same author

Twice-daily and three-times-daily dosing of a repaglinide/metformin fixed-dose combination tablet provide similar glycaemic control.

Diabetes, obesity & metabolism·2009

Glycemic control

Area of Science:

Endocrinology
Genetics
Metabolic Diseases

Background:

The link between glycemic control and diabetic complications is not fully understood.
About 25% of individuals with diabetes do not develop complications, regardless of blood sugar levels.
Genetic factors may play a role in the development of diabetic complications.

Purpose of the Study:

To explore the relationship between glycemic control and diabetic complications.
To investigate the role of genetic factors in diabetic complications.
To determine the optimal glycemic control for preventing or stabilizing diabetic complications.

Main Methods:

Review of epidemiological studies and clinical trials.
Analysis of genetic factors such as HLA type and hypertension predisposition.

Related Experiment Videos

Evaluation of the impact of improved glycemic control on retinopathy, microalbuminuria, and nervous system function.

Main Results:

Improved glycemic control can stabilize early diabetic retinopathy, microalbuminuria, and nervous system function.
Near-normal blood sugar levels improve serum lipoprotein levels.
Genetic predisposition appears to influence the development of diabetic complications.

Conclusions:

The precise degree of glycemic control needed to impact diabetic complications is unknown.
Achieving near-normal blood sugar levels carries risks like severe hypoglycemia and weight gain.
Further research is required to understand the interplay between genetic factors and glycemic control in diabetes management.