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Multicentre collaboration in perinatal trials in Canada.

J M Moutquin¹, W D Fraser

¹Hôpital Saint-François-d'Assise, Department of Obstetrics Gynecology, Laval University, Quebec, Canada.

Early Human Development

|June 1, 1992

Summary

Canadian perinatal investigators united to prioritize preventing and treating prematurity, leading to multicentre clinical trials and a new national research network.

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Area of Science:

Obstetrics and Gynecology
Neonatal Research
Public Health

Background:

The Canadian Ministry of Health requested improved strategies for Canadian health.
Perinatal investigators identified prematurity as a key health concern.
A consensus emerged on the need to treat and prevent preterm birth.

Purpose of the Study:

To outline the collaborative efforts in Canadian perinatal research.
To highlight the focus on addressing prematurity.
To describe the evolution into a permanent clinical trial network.

Main Methods:

Convening perinatal investigators from 16 Canadian university departments.
Designing and executing multicentre clinical trials focused on perinatal interventions.
Establishing a permanent national perinatal clinical trial network.

Main Results:

A consensus was reached on prioritizing prematurity prevention and treatment.
Several multicentre clinical trials on perinatal interventions were conducted over 10 years.
A permanent perinatal clinical trial network with over 100 members was formed.

Conclusions:

Canadian collaboration is effective in advancing perinatal health research.
The established network facilitates ongoing research into prematurity.
Continued focus on perinatal interventions is crucial for improving infant health outcomes.

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