Evaluation of the E test in testing susceptibility of Pseudomonas aeruginosa to tobramycin
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H Rautelin1, I Renkonen, O V Renkonen
1Department of Bacteriology and Immunology, University of Helsinki, Finland.
Abstract:
The E test, a new technique for measuring MICs of antimicrobial agents with the ease of disc diffusion tests, was evaluated in testing the susceptibility of 94 clinical isolates of Pseudomonas aeruginosa to tobramycin. The use of the E test was found acceptable; 93% of the MIC results were within one log2 dilution step and 100% were within two log2 dilution steps when the MICs obtained by the E test were compared to those obtained by the conventional agar dilution method. When the E test was compared to the broth microdilution method the corresponding figures were 84% and 100%, respectively.
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