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A possible mechanism for pacemaker-induced T-wave changes.

L Fu¹, K Imai, A Okabe

¹Cardiovascular Institute, Tokyo, Japan.

European Heart Journal

|September 1, 1992

Summary

This summary is machine-generated.

Pacemaker use can cause T-wave changes and myocardial ischemia. These effects persist after pacing stops, leading to T-wave inversions, suggesting potential cardiac stress from ventricular pacing.

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Area of Science:

Cardiology
Electrophysiology
Medical Imaging

Background:

The cause and impact of T-wave changes induced by pacemakers are not fully understood.
Pacemaker use is common for treating bradyarrhythmias.

Purpose of the Study:

To investigate pacemaker-induced T-wave changes using body surface potential mapping (BSM) and thallium-201 myocardial scintigraphy (T1-SC).
To compare BSM and T1-SC findings before, during, and after ventricular pacing (VP).

Main Methods:

10 patients with bradyarrhythmias underwent BSM and T1-SC during and after VP.
Studies were conducted without medications to isolate pacing effects.

Main Results:

Ventricular pacing induced abnormal dipolar patterns on QRST maps and T-wave inversions.
Resting T1-SC revealed transient myocardial perfusion defects during chronic VP.
Both T-wave abnormalities and perfusion defects persisted for hours after pacing cessation, attenuating over weeks.

Conclusions:

Chronic ventricular pacing may induce myocardial ischemia.
Persistent T-wave abnormalities after pacing cessation are linked to these ischemic changes.