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Phaeohyphomycosis caused by Bipolaris spicifera: an informative case
M R McGinnis1, G Campbell, W K Gourley
1Department of Pathology, University of Texas Medical Branch, Galveston 77555.
European Journal of Epidemiology
|May 1, 1992
Summary
A rare brain and sinus infection caused by Bipolaris spicifera was successfully treated. This case highlights effective surgical and antifungal treatment for phaeohyphomycosis.
Area of Science:
- Mycology
- Infectious Diseases
- Neurology
Background:
- Phaeohyphomycosis is a fungal infection caused by dematiaceous molds.
- Bipolaris species are increasingly recognized as human pathogens.
- Central nervous system involvement in phaeohyphomycosis is rare and often carries a poor prognosis.
Observation:
- A case of phaeohyphomycosis involving the brain and sinuses is presented.
- The causative agent was identified as Bipolaris spicifera.
- The patient presented with neurological symptoms and sinus congestion.
Findings:
- Surgical resection of the infected brain and sinus tissue was performed.
- Systemic ketoconazole therapy was initiated post-operatively.
- The patient showed complete recovery with resolution of both sinus and brain infections.
Implications:
- This case demonstrates the successful management of a rare and potentially fatal fungal infection.
- Combined surgical and medical therapy can be effective in treating Bipolaris-induced central nervous system phaeohyphomycomycosis.
- Early diagnosis and prompt intervention are crucial for favorable outcomes in such cases.