Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Zinc gluconate and the common cold: a controlled clinical study.

J C Godfrey1, B Conant Sloane, D S Smith

  • 1Dartmouth College Health Service, Hanover, New Hampshire.

The Journal of International Medical Research
|June 1, 1992
PubMed
Summary

Zinc supplements may shorten common cold duration when using a specific glycine-based formulation. This study found faster symptom resolution in adults taking zinc compared to placebo.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plant size, latitude, and phylogeny explain within-population variability in herbivory.

Science (New York, N.Y.)·2023
Same author

Comparative safety profile of chloral hydrate versus other sedatives for procedural sedation in hospitalized infants.

Journal of neonatal-perinatal medicine·2020
Same author

Differential Proteomics for Distinguishing Ischemic Stroke from Controls: a Pilot Study of the SpecTRA Project.

Translational stroke research·2018
Same author

Sudden Drowning Syndrome.

The Physician and sportsmedicine·2017
Same author

Successful endoscopic resection of adenocarcinoma arising in an esophageal inlet patch.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2014
Same author

Surgical management of the symptomatic cervical spine in rheumatoid arthritis.

Orthopedics·2014

Area of Science:

  • Pharmacology
  • Immunology

Background:

  • Previous studies on zinc gluconate for common colds yielded conflicting results.
  • Inactivation of zinc in earlier formulations may explain the discrepancies.

Observation:

  • A novel non-chelating zinc formulation with glycine was developed.
  • This formulation releases 93% of zinc into saliva, enhancing bioavailability.

Findings:

  • A randomized, double-blind trial in 73 young adults demonstrated zinc's efficacy.
  • Zinc-treated patients experienced symptom resolution 1.2 days sooner than placebo.
  • Early treatment (within 1 day of onset) showed a more pronounced effect on cold duration.

Implications:

  • Optimized zinc formulations may offer a viable option for managing common cold symptoms.

Related Experiment Videos

  • Further research into zinc's therapeutic potential for upper respiratory infections is warranted.
  • Specific formulations are crucial for achieving therapeutic benefits.