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Characterisation of a novel repetitive DNA sequence from Mycobacterium bovis
T J Doran1, A L Hodgson, J K Davies
1CSIRO Division of Animal Health, Animal Health Research Laboratory, Parkville, Australia.
FEMS Microbiology Letters
|September 15, 1992
Abstract:
We report characterisation of three copies of a novel repeat sequence isolated from a Mycobacterium bovis genomic library. The repeat occurs within open reading frames, potentially encoding a conserved tandem array of a pentapeptide sequence with the consensus X-Gly-Asn-X-Gly. The tandem array is present up to five times in M. bovis and it is proposed that they may occur in a family of genes expressing functionally related proteins. We postulate that these proteins may play a role in binding of M. bovis to host cell receptors.