Related Experiment Video

Updated: Aug 8, 2026

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)
07:13

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)

Published on: March 25, 2016

Teratogenic effect of 5-hydroxytryptamine in mice

E POULSON, J M ROBSON, F M SULLIVAN

    Science (New York, N.Y.)
    |August 23, 1963
    PubMed

    The subcutaneous injection of a single dose of 5-hydroxytryptamine into pregnant mice produced a large number of fetal abnormalities, mostly of the eyes, limbs, and tail; the skull and central nervous system were also sometimes affected. These effects could result from the action of the drug on placental function and blood supply.

    Keywords:
    ABNORMALITIESFETAL DEATHSEROTONIN

    More Related Videos

    Is My Mouse Pregnant? High-Frequency Ultrasound Assessment02:39

    Is My Mouse Pregnant? High-Frequency Ultrasound Assessment

    Published on: March 18, 2021

    Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice04:18

    Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

    Published on: October 10, 2025

    Related Concept Videos

    Teratogenicity01:07

    Teratogenicity

    The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...