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"Carba" peptide bond surrogates. Different approaches to Gly-psi(CH2-CH2)-D,L-Xaa pseudo-dipeptide units
M Rodriguez1, A Heitz, J Martinez
1CCIPE, Faculty of Pharmacy, Montpellier, France.
International Journal of Peptide and Protein Research
|March 1, 1992
Abstract:
Racemic "carba" pseudo-dipeptide units such as Gly-psi(CH2-CH2)-D,L-Xaa were obtained either through the Horner-Emmons condensation of N-tert.-butyloxycarbonyl-beta alaninal with the appropriate substituted triethyl phosphonacetate, or from commercially available 3-carbethoxy-2-piperidone.