Seroprevalence of enteric and nonenteric adenoviruses in Bangladesh

Single serum samples obtained from infants between 0 and 24 months of age admitted to a diarrheal disease hospital in Bangladesh were tested for the presence of adenovirus-specific immunoglobulin G (IgG) and IgA antibodies by using enzyme immunoassay and neutralizing antibodies to adenovirus types 2, 40, and 41. IgG antibodies were more prevalent than IgA antibodies, and neutralizing activity to enteric adenovirus was found in serum samples from 50% of infants who had reached 2 years of age.