Lingual vein injection in the rat

Area of Science:

• Veterinary Science
• Animal Research Methodology

Background:

• Repeated intravenous injections are crucial for many rodent experiments.
• Existing methods for intravenous injections in rodents present significant challenges and limitations.

Purpose of the Study:

• To describe a novel and effective method for repeated intravenous administration in rodents.
• To overcome the limitations associated with traditional intravenous injection techniques in experimental animals.

Main Methods:

• The study utilized the lingual veins of anesthetized rats for intravenous access.
• The described method facilitates repeated administration of fluids and cells.
• The technique was successfully applied to young rats and hamsters.

Main Results:

• A practical method for repeated intravenous injections in rodents was successfully established.
• The lingual vein approach proved effective for delivering fluids and cells.
• The method demonstrated applicability in both young rats and hamsters.

Conclusions:

• The lingual vein injection method offers a viable solution for repeated intravenous access in rodents.
• This technique enhances experimental possibilities by overcoming previous injection-related limitations.
• The method is suitable for young rats and hamsters, broadening its utility in preclinical research.