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Related Experiment Videos

Reactive lentiginous hyperpigmentation after cryosurgery for lentigo maligna.

K Böhler-Sommeregger1, S Schuller-Petrovic, R Knobler

  • 1Department of Dermatology II, University of Vienna, Austria.

Journal of the American Academy of Dermatology
|October 1, 1992
PubMed
Summary
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Cryosurgery for facial lentigo maligna can cause benign hyperpigmentation that mimics recurrence. Histologic evaluation is crucial to distinguish between true lentigo maligna recurrence and benign changes after treatment.

Area of Science:

  • Dermatology
  • Oncology
  • Surgical Procedures

Background:

  • Cryosurgery is a treatment for lentigo maligna.
  • Facial lentigo maligna patients treated with cryosurgery may develop hyperpigmentation.
  • This hyperpigmentation can resemble a recurrence of the condition.

Purpose of the Study:

  • To determine if repigmentation after cryosurgery for lentigo maligna indicates recurrence.
  • To differentiate between benign repigmentation and true lentigo maligna recurrence.

Main Methods:

  • Twenty patients with facial lentigo maligna treated with cryosurgery were monitored.
  • Follow-up ranged from 7 to 80 months with frequent clinical observations.

Main Results:

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  • Eight patients developed lentiginous hyperpigmentation in the treated area.
  • Histologic examination confirmed lentigo maligna recurrence in three patients.
  • Five patients showed benign hyperpigmentation.

    • Conclusions:

    • Benign lentiginous hyperpigmentation can occur after cryosurgery for lentigo maligna.
    • Genetic factors and UV exposure may contribute to benign hyperpigmentation.
    • Histologic assessment is mandatory to rule out lentigo maligna recurrence.