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The cementomas--a clinicopathological re-appraisal
1University of the Witwatersrand, Johannesburg.
Summary
This study reclassifies cemental tumors, proposing "cemento-osseous dysplasia" as a more accurate term for gigantiform cementoma. The findings suggest a revised classification for these jaw lesions.
Area of Science:
- Oral Pathology
- Tumor Biology
- Dental Radiology
Background:
- Cemental tumors present diagnostic challenges.
- Existing classifications may not fully capture the spectrum of these lesions.
- Sub-classification requires clinicopathological correlation.
Purpose of the Study:
- To evaluate the necessity of sub-classifying cemental tumors.
- To define the clinicopathological characteristics of distinct cemental tumor entities.
- To propose an updated classification for cemental lesions.
Main Methods:
- Retrospective analysis of 127 cemental tumor cases.
- Histopathological examination and categorization of lesions.
- Correlation of clinical and pathological findings.
Main Results:
- Identified gigantiform cementoma (84%), cementifying fibroma (12%), and benign cementoblastoma (4%).
- Gigantiform cementoma lesions varied in presentation and occurred predominantly in older Black females.
- Peripheral proliferative areas in gigantiform cementoma mimicked other lesions; infection was common.
- Periapical cemental dysplasia suggested as a variant of gigantiform cementoma.
- Cementifying fibroma proposed as part of the cemento-ossifying fibroma spectrum.
Conclusions:
- Recommends "cemento-osseous dysplasia" as a more appropriate term than gigantiform cementoma.
- Proposes a revised classification: cemento-ossifying fibroma, cementoblastoma, and cemento-osseous dysplasia (with subtypes).
- Highlights the overlap in histopathological features and the need for refined diagnostic criteria.