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Minocycline use discolors teeth.

F M Parkins1, G Furnish, M Bernstein

  • 1Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Louisville, Ky 40292.

Journal of the American Dental Association (1939)
|October 1, 1992
PubMed
Summary
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Minocycline treatment can cause gray striated tooth staining in adults. The tooth discoloration directly correlated with the duration of minocycline therapy.

Area of Science:

  • Dentistry
  • Pharmacology

Background:

  • Minocycline is a widely used antibiotic for various infections.
  • Tooth discoloration is a known side effect of certain medications, particularly tetracyclines.

Observation:

  • A 25-year-old female patient presented with gray striated staining affecting all her teeth.
  • The onset and severity of the tooth staining appeared to correlate with minocycline treatment.

Findings:

  • The patient received minocycline for a period of two years.
  • The observed gray striated staining on the teeth was directly associated with the duration of minocycline administration.

Implications:

  • This case highlights a potential adverse drug reaction of minocycline in adult dentition.

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  • Dental professionals should be aware of minocycline-induced tooth staining when assessing patients with discoloration.
  • Further research may be warranted to understand the mechanism and prevalence of this side effect.