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Maxillary sinus fusariosis in immunocompetent hosts
1Department of ENT, Christian Medical College and Hospital, Vellore, S. India.
Abstract:
We report the first known cases of Fusariosis of maxillary sinus with granuloma and oro-antral fistula in two immunocompetent hosts. Fusarium solani was demonstrated in the direct microscopic examination and isolated in heavy growth from the biopsy materials. Both these patients were successfully treated with oral ketoconazole (200 mg daily) for three weeks followed by a Caldwell-Luc operation. Ketoconazole was continued for two months post-operatively.
Insights
This study details rare cases of maxillary sinus Fusariosis in immunocompetent individuals. Treatment involved ketoconazole and surgical intervention, showing successful outcomes for fungal sinusitis.
Area of Science:
- Mycology
- Otolaryngology
- Infectious Diseases
Background:
- Fusariosis is a fungal infection typically affecting immunocompromised individuals.
- Maxillary sinus involvement is uncommon, especially in immunocompetent hosts.
Observation:
- Two immunocompetent patients presented with maxillary sinus Fusariosis.
- Clinical manifestations included granuloma and oro-antral fistula.
Findings:
- Microscopic examination and culture confirmed Fusarium solani infection.
- Successful treatment involved oral ketoconazole and Caldwell-Luc operation.
Implications:
- This highlights the potential for Fusariosis in immunocompetent hosts.
- Combined antifungal therapy and surgery offer a viable treatment strategy for complex sinus fungal infections.