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Related Experiment Videos

Prototypic sequences for human repetitive DNA.

J Jurka1, J Walichiewicz, A Milosavljevic

  • 1Linus Pauling Institute of Science and Medicine, Palo Alto, CA 94306.

Journal of Molecular Evolution
|October 1, 1992
PubMed
Summary
This summary is machine-generated.

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We present a collection of 53 human genome repetitive element sequences. This dataset includes various repeat types, aiding research into genome structure and function.

Area of Science:

  • Genomics
  • Molecular Biology

Background:

  • The human genome contains numerous repetitive DNA sequences.
  • Understanding these repeats is crucial for genome annotation and analysis.

Purpose of the Study:

  • To curate and provide a standardized collection of prototypic sequences for human repetitive elements.
  • To facilitate research on the structure, evolution, and function of repetitive DNA.

Main Methods:

  • Compilation of 53 prototypic sequences representing known human repetitive element families.
  • Sequences include consensus or representative examples.
  • Annotation and electronic availability of the sequence collection.

Main Results:

  • A comprehensive set of prototypic sequences for diverse repetitive elements is now available.

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  • Included are high/medium reiteration frequency interspersed repeats, endogenous retroviral LTRs, alphoid, and telomere-associated repeats.
  • The collection is electronically accessible for researchers.

    • Conclusions:

    • This curated collection serves as a valuable resource for studying human repetitive elements.
    • It supports further investigations into genome organization and the impact of repeats on genomic stability and evolution.