[Experimental keratoplasty after sensitization by a bacterial antigen (Streptococcus A group)]

Experimental (rabbit) penetrating keratoplasties with donor tissue sensitized to a bacterial antigen (Streptococcus Group A) were placed in normal rabbits and animals sensitized to the same antigen. Severe graft reactions developed two months after grafting in sensitized rabbits while no reaction occurred in controls. It is possible that homograft reactions can be triggered and super-imposed to the immuno-allergice reaction to the foreign antigen present in host and donor.