Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Changes in CSF resorption resistance. Experimental studies].

J Jurkiewicz1, Z Czernicki, J Berdyga

  • 1Kliniki Neurochirurgii ICMDiK PAN, Warszawie.

Neurologia I Neurochirurgia Polska
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Matter-Driven Change of Spacetime Topology.

Physical review letters·2021
Same author

Characteristics of the new phase in CDT.

The European physical journal. C, Particles and fields·2017
Same author

Evaluation of volumetric changes in differential diagnosis of brain atrophy and active hydrocephalus.

Advances in experimental medicine and biology·2014
Same author

Second-order phase transition in causal dynamical triangulations.

Physical review letters·2011
Same author

Analysis of postural sway in patients with normal pressure hydrocephalus: effects of shunt implantation.

European journal of medical research·2010
Same author

What can be found inside shunt catheters.

Acta neurochirurgica. Supplement·2009

Lumbar infusion tests reveal that cerebrospinal fluid outflow resistance is dependent on infusion rate. These findings are crucial for accurate human studies investigating intracranial pressure.

Area of Science:

  • Neuroscience
  • Physiology

Context:

  • Intracranial pressure (ICP) and cerebrospinal fluid (CSF) dynamics are critical in neurological health.
  • Understanding CSF outflow resistance (R) is essential for diagnosing and managing conditions affecting CSF circulation.

Purpose:

  • To investigate the relationship between infusion rates during lumbar infusion tests (IT) and changes in ICP and CSF outflow resistance (R).
  • To compare these dynamics in control subjects versus those with an epidural balloon simulating increased resistance.

Summary:

  • Lumbar infusion tests were conducted at varying rates (0.06-1.2 ml/min) in control animals and animals with an epidural balloon.
  • Both groups showed significant changes in ICP and R, particularly after high infusion rates, with delayed changes observed in the balloon group.
  • Results indicate that CSF outflow resistance (R) is specific to the applied infusion rate.

Related Experiment Videos

Impact:

  • The study highlights that CSF outflow resistance (R) is rate-dependent.
  • This rate-specificity must be considered in human studies involving lumbar infusion tests for accurate interpretation of ICP and R values.
  • Findings have implications for the clinical assessment of CSF disorders.