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OXIDATION OF CARBON-14-LABELED ENDOGENOUS LIPIDS BY ISOLATED PERFUSED RAT HEART
Science (New York, N.Y.)
|January 24, 1964
Abstract:
Lipids of the rat heart were labeled with carbon-14 in vivo. The production of C(14)O(2) during the subsequent perfusion of these glycogen-depleted hearts with buffer, but without added substrate, provided direct evidence of the oxidation of endogenous heart lipids. The net decrease in phospholipid content alone could account for 75 percent of the total metabolic CO(2) formed.
