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ANTIBODY SUPPRESSION BY ANTIGEN HEAVILY LABELED WITH IODINE-131
Antibody formation in rabbits was suppressed by tobacco mosaic virus heavily labeled with iodine-131. Animals were injected intravenously with virus containing 0.5 to 4.4 mc of l(131) and after a period of 6 days were challenged with a new antigen, gammaglobulin. Most irradiated animals did not produce detectable antibody. No signs of radiation sickness were noted.
Antibody formation in rabbits was suppressed by tobacco mosaic virus heavily labeled with iodine-131. Animals were injected intravenously with virus containing 0.5 to 4.4 mc of l(131) and after a period of 6 days were challenged with a new antigen, gammaglobulin. Most irradiated animals did not produce detectable antibody. No signs of radiation sickness were noted.
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